K9 Advantix II

Item #0040155

$29.99 to $69.99

K9 Advantix II

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K9 Advantix II is a once-a-month topical tick, mosquito and flea treatment for dogs and puppies 7 weeks of age or older. Read More

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Featured Advice from Our Experts


Canine Wellness Series - Part 3 - Zoonotic Diseases... What can I catch?

At one time or another, most of us have watched our dogs have a bout of the sniffles or diarrhea. Many of us have wondered if we, too, were at risk of getting sick. Diseases that are passed from animals to humans are zoonotic illnesses. The most well known and most feared zoonotic disease is rabies. Read More...


K9 Advantix II

Offering broad spectrum protection that not only kills but repels fleas, ticks, and mosquitoes, this convenient once a once-a-month topical treatment is for dogs and puppies 7 weeks of age or older and weighing 4 lb or more. Containing Imidacloprid and Permethrin plus the insect growth regulator Pyriproxyfen, these ingredients work in unison to repel and kill parasites that can potentially carry diseases.

Features & Benefits of K9 Advantix II:

  • repels and kills ticks, mosquitoes and fleas for up to four weeks
  • repels and kills fleas of all life stages within 12 hours
  • prevents development of fleas for up to four weeks
  • repels biting flies
  • kills chewing lice
  • waterproof
Do not use on cats.

Note: For maximum effectiveness, you should not bathe your pet 48 hours before or after application. The oils of the skin and coat help to distribute the product properly, ensuring that the product will be effective.

View K9 Advantix II manufacturer and label information - Small Dog

View K9 Advantix II manufacturer and label information - Medium Dog

View K9 Advantix II manufacturer and label information - Large Dog

View K9 Advantix II manufacturer and label information - X-Large Dog

If you find a lower price on a product, with an identical brand and model number, Jeffers will match the competitior's price!

Call for details! (800)533-3377


  • Brand: Bayer Animal Health
  • Type: Flea & Tick
  • Form: Spot-On

Reviews (26)

Write A Review

  1. 5.0 out of 5 stars

    "works great here in the South"

    ...where we have fleas all year round. I have 5 dogs ranging in weight from 4.9 lbs - 135 lbs. Plus various dogs coming in to show. No fleas, no ticks, no coat issues and I just can't have coat problems on a top ranked show dog!!!

  2. 5.0 out of 5 stars

    "It does it all"

    I like having a pest control that does it all. Makes it easier to remember to do their treatments once a month. With the other ones I have to buy another control for heartworm.

  3. 5.0 out of 5 stars

    "k9 advantix II"

    I reviewed it before, and I can say IT REALLY WORKS!! I hope it continues to work well. JE T Jr Laurens, SC..

  4. 5.0 out of 5 stars

    "K9 Advantix II"

    I've used this stuff since I discovered it several years ago. It does the job well, plus it covers one more pest most others don't. Mosquito's. The price might seem high but that more than makes up for the fact I don't have to buy the extra repellent.. I use both the small dog one and the large one, and I've never had a problem with it.

  5. 3.0 out of 5 stars

    "Not all that good"

    Extremely expensive product. One would expect it to work fantastically for what it costs! At $80 I had expected much more! I have five dogs. I will be looking for a better brand which works.

  6. 5.0 out of 5 stars

    "k9 advantix II"

    (I used Frontline for years with great success, however this past year it has not worked..tiny fleas, cat fleas? on my dogs. BUT this K9 ADVANTIX II is working GREAT!! I suppose the fleas have become immune to the Frontline and the others I have tried. Expensive, compared to others BUT WORTH IT!! James PS: How are things "Down Home" have kin-folks down there.

  7. 5.0 out of 5 stars

    "Just once a month"

    All I have to do is remember my Advantix II once a month and it protects my dogs against everything. All the pests including mosquito's. How easy is that???

  8. 5.0 out of 5 stars

    "Best & Safest flea control"

    I've been a Rescue for 40 years. Nothing works better than K9 Advantix (from the original). I won't use anything else!

  9. 5.0 out of 5 stars


    I bought thius exact product at Petsmart for 70 dollatrs. I went to walmart and found exact same thing for 50. I took the petsmart product back now i find thisfor 29 . thats worth ordering for.

  10. 5.0 out of 5 stars


    The best flea prevention treatment by far!! I have 2 dogs and a cat. Advantage keeps them all completely flea and tick free!

  11. 5.0 out of 5 stars

    "advantix 2"

    I love it on my dogs we live in the country with lots of trees, and bushes, I don't have to worry, about anything.

  12. 5.0 out of 5 stars

    "Doesn't work"

    Didn't do what it said. Didn't kill the fleas or control them at all stages. My poor dog has rubbed the hair off her back where it was applied....switching to something else.

  13. 5.0 out of 5 stars

    "Shihtzu Man"

    Best product on the market.

  14. 5.0 out of 5 stars

    "Worth Every Penny..."

    K9 Advantix II is worth every single penny, and then some. Since moving to Missouri, I've always used Frontline Plus. It's an OK product but it does NOT repel anything and I was constantly finding ticks all over Chico (my Shih Tzu) and they were attaching themselves to him. Every single time he would go outside I found ticks that were very much alive. Too creepy for me! So this year I was determined to try something new, that's how I found out about K9 Advantix II. It works like a charm!!Since September of 2012 I have not had one single tick on my dog, not one. This product also repels and kills: mosquito, fleas and other insects. It's a little more expensive but it's worth it. We live in a very wooded area that is prime for ticks so having a product like this is a awesome. I highly recommend it to anyone who is looking to replace FrontLine Plus. I don't usually get so excited about products but I felt I had to share my personal experience. Good luck and I hope you love K9 Advantix II as much as I do.

  15. 5.0 out of 5 stars

    "Wonderful Product"

    "We had moved into a new area almost a year ago. At our former location, we never had a real problem with fleas. That changed this year! Having 7 dogs to treat, I tried the ""cheap"" way. I bought the ""groomer's pack"" which was a waste of money. I tried sprays, shampoos then THIS! I purchased the 55 lb. and over package. Two tubes treated all of my doxies (6) and my pug. I treated them in the evening. The next morning I changed their bedding. I couldn't believe all of the dead fleas on their blankets! This stuff works and I will NEVER waste my time and money on anything else!"

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